Archive for category Research

Chemoimmunotherapy: A New Strategy for the Mesothelioma Treatment

Whether or not the immune system can recognize malignant (cancerous) and pre-malignant cells and eliminate them to prevent the development of cancer is currently under investigation within the medical community and the evidence is favoring the concept.

According to a 2009, study conducted by investigators McCoy, et al. and published in Tissue Antigens, chemoimmunotherapy has become the most recent strategy for the treatment of cancerous mesothelioma.  Chemoimmunotherapy is a treatment strategy that combines chemotherapy, which uses different drugs to kill or slow the growth of cancer cells with immunotherapy, which uses treatments to restore the ability of the immune system to fight cancer.

This recent study has revealed the fact that a cancer such as mesothelioma has been found to effectively interact with the immune system and this makes it a good candidate for immunotherapy.   Several immunotherapies have been investigated to date and the investigators have determined that immunotherapy should be combined with conventional chemotherapy, surgery and radiotherapy as a treatment method that is proving itself, although modestly, to be effective.

The investigators are gearing up to begin a Phase I clinical trial using immunotherapy combined with chemotherapy as it is becomes more and more clear that careful drug selection, dosing and scheduling will be significant when designing a chemoimmunotherapy for mesothelioma.

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Increased Survival in Lung Cancer Patients

The Lancet published a study on Monday showing a increased survival rate for patients with lung cancer.  The study revealed patients suffering from nonsquamous non-small cell lung cancer (NSCLC) who were treated with Alimta and best supportive care on the average had over five months increased survival than patients who received the placebo plus best supportive care after the received initial chemotherapy.

This study is important because it suggests maintenance therapy as a regular practice and highlights the important of histology in choosing treatment options for nonsquamous NSCLC patients.  Maintenance therapy is used with other types of cancer, but is not standard practice for non-small cell lung cancer.  Histologies refer to the various tumor types which fall under the NSCLC category.

Read the about the study:  Significant Survival Benefit for Patients Facing Deadly Form of Lung Cancer

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New Breath Test May Detect Lung Cancer

A new breath test may be able to detect lung cancer according to a new study by scientists in Israel.  This new research could be quicker, easier and have a decreased cost for diagnosing lung cancer.  The test may also allow for earlier detection which increases a patients odds of survival.  The team is hoping their results can be extended to include diagnosing other forms of cancer.

Given that 1.3 million people worldwide die of lung cancer each year according to the World Health Organization, this could have widespread impact on the patients themselves and the healthcare systems.

With each new study I am hopeful we are coming closer to earlier detection/diagnosis and better treatment for lung cancer patients.

Read more about the study – Breathalyzer test detects lung cancer: study

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New Test May Diagnose Mesothelioma More Effectively

Researchers at Oxford University have developed a test that may diagnose mesothelioma more effectively.  Dr. Helen Davies worked on the research and claims it may be a way for medical providers to diagnose cases of mesothelioma earlier.  This could benefit the mesothelioma community in several ways:  medical providers may be able to diagnose earlier and begin appropriate treatment, victims may experience better quality of life and increased life expectancy, and claims for worker’s compensation may begin earlier.

Read the complete article from BCC:  “Better” test for asbestos cancer

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Distribution plan for miRview meso test (Mesothelioma diagnosis test)

Rosetta Genomics (the developer of the test) and Warnex Medical Laboratories (a life science company that provides services to the pharmaceutical and healthcare industries) announced an exclusive distribution agreement for Rosetta’s diagnostic tests.  One of these tests is the miRview meso test which uses microRNA molecular technology to differentiate mesothelioma from other cancers in the lung.  The use of this new test could mean more accurate diagnosis and more efficient  treatment options for mesothelioma patients.

As a provider, I find myself hopeful when reading about new research and diagnostic tools for mesothelioma and other cancers.  I feel we are getting closer to better diagnostic tools, more effective treatments, higher quality of life, and my clients living longer.  I look forward to hearing more about this new test and the implications for the mesothelioma community.

Read more:  Rosetta Genomics and Warnex Medical Laboratories Announce Exclusive Distribution Agreement for Rosetta’s microRNA-based Assays in Canada

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